Director, Antibody Discovery & Protein Engineering
Company: SystImmune
Location: Redmond
Posted on: August 6, 2022
Job Description:
Located in Redmond WA, Systimmune Inc. is a bio-pharmaceutical
company focused on the treatment of cancer through developing novel
therapeutic multi-specific antibodies, as well as antibody-drug
conjugates (ADCs). Our objective is to create biologics that work
through systematic intervention on the solid tumor
micro-environment, to either directly attack the tumor and/or to
activate the immune system to attack the tumor. Summary: The
Director, Antibody Discovery & Protein Engineering will be
responsible for leading a group of scientists to design, immunize,
engineer and characterized antibody drug candidates - in the format
of ADC, bispecific and multi-specific antibodies. Essential Duties
and Responsibilities:
- Lead the antibody discovery and protein engineering
technologies,
- Oversee the integration of new antibody drug development
technologies with novel antibody formats
- Responsible for antibody discovery immunization strategy and
candidate validation
- Lead antibody humanization and engineering for novel
therapeutic multi-specific antibodies and Antibody Drug Conjugates
(ADCs).
- Use structural and sequence analysis to guide the design of
drug candidates
- Oversee drug candidate optimization, selection, validation, and
stability study
- Contributions to regulatory filings of biotherapeutics
- Review and authorize Standard Operating Procedures (SOP)
- Prepare reports and papers of completed projects for
publication in technical journals, patents, presentation to
regulatory agencies or at conferences, or use in further research
activities.
- Support and closely work with other departments
- Work with R&D center in China. Plan time to accommodate
meetings and technical support with team members in China
- Support scientific discussions, high-level strategic scientific
advice, inputs, and expertise to management, the Board, advisory
groups, and scientific committees.
- Participate in timeline planning and decision-making regarding
research priorities of company or department and provide
information on feasibility of prospective projects.
- Other duties as assigned. Qualifications:To perform this job
successfully an individual must be able to perform each essential
duty satisfactorily. The requirements listed below are
representative of the knowledge, skill, and/or ability required.
Reasonable accommodations may be made to enable individuals with
disabilities to perform essential functions.
Keywords: SystImmune, Redmond , Director, Antibody Discovery & Protein Engineering, Executive , Redmond, Washington
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