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Scientist - Antibody Discovery

Company: SystImmune
Location: Redmond
Posted on: May 6, 2022

Job Description:

Located in Redmond WA, Systimmune Inc. is a biopharmaceutical company focused on the treatment of cancer through developing novel therapeutic multi-specific antibodies, as well as antibody-drug conjugates (ADCs). Our objective is to create biologics that work through systematic intervention on the solid tumor micro-environment, to either directly attack the tumor and/or to activate the immune system to attack the tumor.

Summary:
SystImmune is seeking a highly motivated Scientist who will contribute to the discovery of novel antibody therapeutics. This position will participate in the development and advancement of cancer therapeutics. The successful candidate will contribute to all aspects of antibody discovery, from designing immunization campaigns to therapeutic lead selection.

Essential Duties and Responsibilities:
Support therapeutic antibody lead selection using multiple antibody discovery platforms
Design and execute immunization campaigns for specific immuno-oncology targets
Work in a fast-paced team environment to identify antibodies to desired targets within company timelines
Perform multiparametric flow cytometric analysis of mammalian cells in a high-throughput manner
Ability to perform fluorescence-based sorting of yeast and mammalian cells
Prepare and generate yeast display libraries for the selection of antibodies against desired targets
Assist with routine maintenance and operation of cell sorter
Use a variety of methods to determine antibody kinetics, affinity, and specificity
Prioritize work on multiple projects, support, and closely work with other divisions to advance company goals
Plan experiments, outline research procedures to be followed, and provide training to subordinate personnel to carry out research
Ability to follow Standard Operating Procedures and effectively document and present results to colleagues
Work with other internal research departments and development groups in China. Plan time to accommodate meetings and technical support
Other duties as assigned

Qualifications:
To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Education/Experience
Ph.D. degree with additional 1 or more years of antibody discovery or relevant experience . E xperience with B cell oriented research OR building and evaluating yeast display libraries is highly desirable . Background in flow cytometry and cell sorting is very valuable. History of research involving RNA extraction and cloning desirable, but not required.

Keywords: SystImmune, Redmond , Scientist - Antibody Discovery, Other , Redmond, Washington

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